Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585687 | 0.91 | EGLN1 (0.56) | EGLN1EGLN3 | |
| SCHEMBL1586363 | 0.85 | EGLN1 (0.50) | EGLN1EGLN3HIF1AMEN1MAPT | |
| SCHEMBL1585642 | 0.85 | EGLN1 (0.50) | EGLN1EGLN3 | |
| SCHEMBL1585836 | 0.85 | EGLN1 (0.48) | EGLN1EGLN3HIF1AMEN1ALDH1A1 | |
| SCHEMBL1585761 | 0.84 | EGLN1 (0.53) | EGLN1EGLN3 | |
| SCHEMBL1585825 | 0.84 | EGLN1 (0.48) | EGLN1EGLN3 | |
| SCHEMBL1586373 | 0.82 | EGLN3 (0.45) | EGLN1EGLN3HIF1AALDH1A1MAPT | |
| SCHEMBL1585792 | 0.82 | KDM4E (0.48) | EGLN1EGLN3HIF1AKDM4EMEN1 | |
| SCHEMBL1586485 | 0.82 | EGLN1 (0.47) | EGLN1EGLN3HIF1A | |
| SCHEMBL1585822 | 0.82 | EGLN1 (0.47) | EGLN1EGLN3HIF1AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |