Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586015 | 0.92 | EGLN1 (0.45) | EGLN1SMN1; SMN2HIF1ALMNABBOX1 | |
| SCHEMBL1586241 | 0.90 | KDM4E (0.47) | EGLN1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL1586450 | 0.89 | EGLN1 (0.44) | EGLN1SMN1; SMN2HIF1ALMNAHTT | |
| SCHEMBL1585687 | 0.88 | EGLN1 (0.56) | EGLN1EGLN3 | |
| SCHEMBL1585620 | 0.87 | EGLN1 (0.48) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL1585869 | 0.86 | EGLN1 (0.47) | EGLN1KDM4ESMN1; SMN2HIF1ALMNA | |
| SCHEMBL1585825 | 0.85 | EGLN1 (0.48) | EGLN1SMN1; SMN2BBOX1ASPHKDM8 | |
| SCHEMBL1586363 | 0.85 | EGLN1 (0.50) | EGLN1HIF1AMEN1KMT2AEGLN3 | |
| SCHEMBL1585836 | 0.85 | EGLN1 (0.48) | EGLN1HIF1ABBOX1ASPHKDM8 | |
| SCHEMBL1585642 | 0.85 | EGLN1 (0.50) | EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |