Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 19/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859363 | 0.91 | FFAR3 (0.57) | FFAR3KDM4E | |
| SCHEMBL15859396 | 0.86 | FFAR3 (0.62) | FFAR3KDM4EGPR174 | |
| SCHEMBL15859429 | 0.86 | FFAR3 (0.61) | FFAR3KDM4E | |
| SCHEMBL5064697 | 0.86 | FFAR3 (0.79) | FFAR3KDM4E | |
| SCHEMBL15859398 | 0.83 | FFAR3 (0.75) | FFAR3KDM4E | |
| SCHEMBL15859458 | 0.81 | FFAR3 (0.56) | FFAR3KDM4E | |
| SCHEMBL15859333 | 0.80 | FFAR3 (0.74) | FFAR3KDM4E | |
| SCHEMBL5061501 | 0.77 | FFAR3 (0.75) | FFAR3KDM4E | |
| SCHEMBL5238694 | 0.76 | GPR174 (0.57) | FFAR3KDM4EGPR174 | |
| SCHEMBL3263109 | 0.73 | FFAR3 (0.84) | FFAR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812080-B1 | GPR41 AND MODULATORS THEREOF FOR THE TREATMENT OF INSULIN-RELATED DISORDERS | ARENA PHARM INC (US) | 2014-07-09 | — | — | EP | claimed |