Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65066 | 0.83 | HSP90AA1 (0.50) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL23351367 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL7933455 | 0.81 | MEN1 (0.47) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| Bromide SCHEMBL6879691 | 0.81 | HSP90AA1 (0.49) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL9061399 | 0.81 | HSP90AA1 (0.49) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL52556 | 0.74 | MEN1 (0.41) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL13883829 | 0.73 | MEN1 (0.46) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8310392 | 0.72 | MEN1 (0.45) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL25575731 | 0.72 | MEN1 (0.40) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL18065654 | 0.71 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014105662-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-07-03 | — | — | WO | disclosed |