Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623615 | 0.75 | CA2 (0.39) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL11533016 | 0.75 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL9869478 | 0.75 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL9869485 | 0.75 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL65066 | 0.75 | HSP90AA1 (0.50) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL23351367 | 0.75 | MEN1 (0.49) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| Bromide SCHEMBL6879691 | 0.73 | HSP90AA1 (0.49) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9061399 | 0.73 | HSP90AA1 (0.49) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7933455 | 0.73 | MEN1 (0.47) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL20109332 | 0.72 | MEN1 (0.51) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685475-B1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1999-01-13 | — | — | EP | disclosed |
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0685475-A1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |