Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138552 | 0.88 | KMT2A (0.67) | KMT2AUSP2HPGDTSHRCYP1A2 | |
| SCHEMBL28896761 | 0.77 | CRHBP (0.43) | KMT2AHPGDCYP1A2CYP3A4IGF1R | |
| SCHEMBL29211280 | 0.73 | CRHBP (0.40) | KMT2AHPGDCYP1A2CYP3A4IGF1R | |
| SCHEMBL14398401 | 0.72 | KMT2A (0.51) | KMT2AUSP2HPGDTSHRCYP1A2 | |
| SCHEMBL21296716 | 0.72 | MAPK1 (0.46) | KMT2AHPGDTSHRCYP1A2CYP3A4 | |
| SCHEMBL6831526 | 0.71 | KMT2A (0.43) | KMT2AUSP2HPGDTSHRCYP1A2 | |
| SCHEMBL18608207 | 0.71 | CA1 (0.63) | KMT2AHPGDCYP1A2CYP3A4MAPK1 | |
| SCHEMBL6835420 | 0.70 | KMT2A (0.41) | KMT2AUSP2HPGDCYP1A2CYP3A4 | |
| SCHEMBL11363402 | 0.69 | KMT2A (1.00) | KMT2AUSP2HPGDTSHRCYP1A2 | |
| SCHEMBL24392210 | 0.68 | KMT2A (0.45) | KMT2AUSP2HPGDTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |