SCHEMBL1586535

SCHEMBL1586535

Cn1c(=O)c(C(=O)NCC(=O)O)c(O)c2cc3ccc(S(C)(=O)=O)cc3n21

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 17/20 0.46
EGLN1 Q9GZT9 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1586084 0.86 EGLN1 (0.48) HIF1AEGLN1
SCHEMBL1585770 0.83 ALDH1A1 (0.38) EGLN1
SCHEMBL1585769 0.83 ALDH1A1 (0.38) EGLN1
SCHEMBL1586308 0.83 HIF1A (0.55) HIF1AEGLN1
SCHEMBL1585695 0.82 EGLN1 (0.45) HIF1AEGLN1
SCHEMBL1586493 0.82 EGLN1 (0.47) HIF1AEGLN1
SCHEMBL1586238 0.82 HIF1A (0.54) HIF1AEGLN1
SCHEMBL1586629 0.82 EGLN1 (0.46) HIF1AEGLN1
SCHEMBL1586428 0.82 EGLN1 (0.49) HIF1AEGLN1
SCHEMBL1585562 0.80 EGLN1 (0.51) HIF1AEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011048611-A1 NOVEL FUSED PYRIDAZINE DERIVATIVES TORRENT PHARMACEUTICALS LIMITED (IN) 2011-04-28 WO claimed