SCHEMBL15866565

SCHEMBL15866565

CCC(C)(CCO)OC(=O)Nc1ccc(C)c(NC(=O)Nc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
LMNA P02545 4/20 0.46
ATM Q13315 1/20 0.46
DDX3X O00571 2/20 0.44
KCNJ6 P48051 1/20 0.43
KCNJ5 P48544 1/20 0.43
KCNJ3 P48549 1/20 0.43
RAB9A P51151 3/20 0.42
MAPK1 P28482 2/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 3/20 0.41
PKM P14618 1/20 0.41
ALDH1A1 P00352 1/20 0.41
IDH1 O75874 4/20 0.41
ITGB1 P05556 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15866558 0.86 MAPT (0.46) MAPTKMT2AMEN1LMNAATM
SCHEMBL15866560 0.84 MAPT (0.43) MAPTKMT2AMEN1LMNAATM
SCHEMBL4016652 0.84 MAPT (0.54) MAPTKMT2AMEN1LMNAATM
SCHEMBL13593479 0.81 LMNA (0.53) MAPTKMT2AMEN1LMNAATM
SCHEMBL13104532 0.81 MAPT (0.59) MAPTKMT2AMEN1LMNAATM
SCHEMBL13593044 0.80 LMNA (0.55) MAPTKMT2AMEN1LMNAATM
SCHEMBL13104526 0.79 MAPT (0.59) MAPTKMT2AMEN1LMNAATM
SCHEMBL13104614 0.79 MAPT (0.68) MAPTKMT2AMEN1LMNAATM
SCHEMBL13104582 0.78 MAPT (0.55) MAPTKMT2AMEN1LMNAATM
SCHEMBL13104527 0.78 MAPT (0.53) MAPTKMT2AMEN1LMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1260498-B1 NOVEL COLOR FORMER AND RECORDING MATERIAL CHEMIPRO KASEI KAISHA LTD (JP) 2014-07-09 EP disclosed