Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | BRS3 | P32247 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948776 | 0.91 | TSHR (0.36) | TSHRS1PR1PTGESL3MBTL1BRS3 | |
| SCHEMBL9948774 | 0.91 | TSHR (0.36) | TSHRS1PR1PTGESL3MBTL1BRS3 | |
| SCHEMBL15869687 | 0.91 | TSHR (0.37) | TSHRS1PR1L3MBTL1WNT3AFAAH | |
| SCHEMBL15869621 | 0.90 | TSHR (0.39) | TSHRS1PR1L3MBTL1WNT3AFAAH | |
| SCHEMBL15869622 | 0.90 | TSHR (0.39) | TSHRS1PR1L3MBTL1WNT3AFAAH | |
| SCHEMBL9947939 | 0.81 | TSHR (0.38) | TSHRS1PR1BRS3WNT3AFAAH | |
| SCHEMBL9947933 | 0.81 | TSHR (0.38) | TSHRS1PR1BRS3WNT3AFAAH | |
| SCHEMBL9947942 | 0.81 | TSHR (0.38) | TSHRS1PR1BRS3WNT3AFAAH | |
| SCHEMBL9947919 | 0.81 | TSHR (0.40) | TSHRS1PR1BRS3WNT3AFAAH | |
| SCHEMBL9947916 | 0.81 | TSHR (0.40) | TSHRS1PR1BRS3WNT3AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778954-B2 | Phenylpyridine derivative and medicinal agent comprising same | KOWA COMPANY, LTD. (JP) | 2014-07-15 | — | — | US | disclosed |