Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869747 | 1.00 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1992104 | 1.00 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL1987276 | 0.87 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL1985445 | 0.86 | MCHR1 (0.40) | SIGMAR1 | |
| SCHEMBL1988645 | 0.84 | CFTR (0.34) | SIGMAR1 | |
| SCHEMBL1986075 | 0.83 | CFTR (0.35) | SIGMAR1 | |
| SCHEMBL1985447 | 0.82 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL1985449 | 0.80 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL1985516 | 0.79 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL1985618 | 0.79 | SIGMAR1 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778959-B2 | AZA-bridged ring-fused indoles and indolines | ABBVIE INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-8778959-B2 | AZA-bridged ring-fused indoles and indolines | ABBVIE INC. (US) | 2014-07-15 | — | — | US | disclosed |