Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227020 | 0.80 | — | — | |
| SCHEMBL589814 | 0.78 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL3829607 | 0.76 | HDAC1 (0.38) | — | |
| SCHEMBL3830936 | 0.76 | HDAC1 (0.38) | — | |
| SCHEMBL1147539 | 0.76 | — | — | |
| SCHEMBL1184758 | 0.75 | — | — | |
| SCHEMBL2730288 | 0.75 | P2RY13 (0.40) | — | |
| SCHEMBL5909366 | 0.75 | — | — | |
| SCHEMBL4215677 | 0.74 | BACE1 (0.33) | — | |
| SCHEMBL5909459 | 0.74 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014108832-A1 | ANTIBACTERIAL OXAZOLONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2014-07-17 | — | — | WO | disclosed |