⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113895 | 1.00 | — | — | |
| SCHEMBL15873305 | 1.00 | — | — | |
| SCHEMBL15875677 | 1.00 | — | — | |
| SCHEMBL16522617 | 0.89 | SPHK1 (0.36) | — | |
| SCHEMBL14213005 | 0.89 | SPHK1 (0.36) | — | |
| SCHEMBL22115984 | 0.87 | — | — | |
| SCHEMBL16504789 | 0.87 | — | — | |
| SCHEMBL15873310 | 0.87 | — | — | |
| SCHEMBL16504804 | 0.87 | — | — | |
| SCHEMBL21768526 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943485-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | Incyte Corporation (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014110574-A1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-17 | — | — | WO | disclosed |