⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15872867 | 1.00 | — | — | |
| SCHEMBL3218658 | 0.88 | SPHK1 (0.40) | — | |
| SCHEMBL3218663 | 0.88 | SPHK1 (0.40) | — | |
| SCHEMBL28856810 | 0.88 | SPHK1 (0.40) | — | |
| SCHEMBL16504650 | 0.85 | — | — | |
| SCHEMBL15872754 | 0.85 | — | — | |
| SCHEMBL20357915 | 0.85 | — | — | |
| SCHEMBL20357914 | 0.85 | — | — | |
| SCHEMBL15873305 | 0.84 | — | — | |
| SCHEMBL21113895 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945939-B1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2020-03-04 | — | — | EP | disclosed |