⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17022778 | 0.97 | MEN1 (0.52) | — | |
| SCHEMBL4100687 | 0.97 | MEN1 (0.57) | — | |
| SCHEMBL4099737 | 0.97 | MEN1 (0.57) | — | |
| Hydrochloric Acid SCHEMBL17022779 | 0.95 | MEN1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL17022787 | 0.95 | MEN1 (0.55) | — | |
| SCHEMBL1176598 | 0.92 | — | — | |
| SCHEMBL28962503 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL17022791 | 0.90 | — | — | |
| Arcaine SCHEMBL303546 | 0.89 | MEN1 (0.62) | — | |
| Sulfuric Acid SCHEMBL17022790 | 0.86 | ALOX15 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | claimed |
| WO-2022237798-A1 | BENZOYLGUANIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛海洋生物医药研究院 | 2022-11-17 | — | — | WO | claimed |
| CN-115317474-A | Application of benzoylguanidine derivative in preparation of medicine for preventing and treating nervous system diseases or cardiovascular system diseases | 中国海洋大学 | 2022-11-11 | — | — | CN | claimed |
| CN-122005450-A | Drug-loaded nano micelle and preparation method and application thereof | 河南中医药大学 | 2026-05-12 | — | — | CN | disclosed |
| CN-118307583-A | Beta amino ester, poly beta amino ester compound, preparation method and application thereof | 上海科技大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-117771307-A | Medicated bath composition, medicated bath bag, and preparation method and application method thereof | 陕西华清宫文化旅游有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115073329-B | Novel leonurine derivative and preparation method and application thereof | 中国海洋大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-113967206-B | Application of leonurine in medicine for treating polycystic ovarian syndrome | 中国农业大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022237798-A1 | BENZOYLGUANIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛海洋生物医药研究院 | 2022-11-17 | — | — | WO | disclosed |
| CN-115317474-A | Application of benzoylguanidine derivative in preparation of medicine for preventing and treating nervous system diseases or cardiovascular system diseases | 中国海洋大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-1065527-C | Guanidine derivatives, process for producing granidine derivatives and cosmetics containing guanidine derivatives | KAO CORP (JP) | 2001-05-09 | — | — | CN | disclosed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-1022276-A1 | EPOXYSUCCINAMIDE DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5939078-A | TREATING WRINKLES BY ADMINISTERING TO THE SKIN A GUANIDINE DERIVATIVE | KAO CORPORATION (JP) | 1999-08-17 | — | — | US | disclosed |
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| CN-1166135-A | Cosmetic compsns. | KAO CORP (JP) | 1997-11-26 | — | — | CN | disclosed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
| CN-1127249-A | Guanidine derivatives, process for producing granidine derivatives and cosmetics containing guanidine derivatives | KAO CORP (JP) | 1996-07-24 | — | — | CN | disclosed |