Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875832 | 1.00 | PIK3CD (0.44) | PIK3CDLMNAMAPTTHRBSOS1 | |
| SCHEMBL714203 | 0.92 | MAPT (0.42) | PIK3CDLMNAMAPTSOS1MTNR1B | |
| SCHEMBL714202 | 0.92 | MAPT (0.42) | PIK3CDLMNAMAPTSOS1MTNR1B | |
| SCHEMBL714201 | 0.90 | PIK3CD (0.55) | PIK3CDALDH1A1 | |
| SCHEMBL15875814 | 0.90 | PIK3CD (0.55) | PIK3CDALDH1A1 | |
| SCHEMBL17530769 | 0.84 | MAPT (0.45) | LMNAMAPTSOS1ALDH1A1MTNR1B | |
| SCHEMBL715035 | 0.82 | CNR2 (0.44) | PIK3CDSOS1ALDH1A1KIT | |
| SCHEMBL715036 | 0.82 | CNR2 (0.44) | PIK3CDSOS1ALDH1A1KIT | |
| SCHEMBL715529 | 0.82 | MAPT (0.47) | PIK3CDLMNAMAPTTHRBALDH1A1 | |
| SCHEMBL715528 | 0.82 | MAPT (0.47) | PIK3CDLMNAMAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | claimed |
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |