Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530781 | 0.91 | ALDH1A1 (0.42) | MAPTTP53MTNR1BLMNAPIK3CA | |
| SCHEMBL17530766 | 0.90 | MAP4K4 (0.40) | MAPTTP53LMNAOPRK1KDM4E | |
| SCHEMBL15875835 | 0.84 | PIK3CD (0.44) | MAPTMTNR1BLMNAALDH1A1SOS1 | |
| SCHEMBL15875832 | 0.84 | PIK3CD (0.44) | MAPTMTNR1BLMNAALDH1A1SOS1 | |
| SCHEMBL714203 | 0.82 | MAPT (0.42) | MAPTMTNR1BLMNAPIK3CAMTOR | |
| SCHEMBL714202 | 0.82 | MAPT (0.42) | MAPTMTNR1BLMNAPIK3CAMTOR | |
| SCHEMBL17530765 | 0.81 | ALDH1A1 (0.40) | MAPTTP53MTNR1BLMNAKDM4E | |
| SCHEMBL17530859 | 0.80 | KIT (0.40) | — | |
| SCHEMBL17530813 | 0.79 | KIT (0.39) | MEN1KMT2A | |
| SCHEMBL17530787 | 0.78 | DPP4 (0.37) | OPRK1PIK3CAMTORSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |