Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875897 | 0.84 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL3759166 | 0.83 | CRHR1 (0.73) | CRHR1 | |
| SCHEMBL3746202 | 0.70 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3666933 | 0.70 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL3754071 | 0.69 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL3668220 | 0.68 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL3751403 | 0.67 | CRHR1 (0.77) | CRHR1 | |
| SCHEMBL3760990 | 0.63 | CRHR1 (0.87) | CRHR1 | |
| SCHEMBL3756720 | 0.62 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL3756348 | 0.62 | CRHR1 (0.84) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785460-B2 | Tricyclic compounds and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-22 | — | — | US | claimed |