Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378842 | 0.80 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| SCHEMBL29366806 | 0.80 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| Ammonia Solution, Strong SCHEMBL3860163 | 0.78 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| Ammonia Solution, Strong SCHEMBL28099769 | 0.78 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| Ammonia Solution, Strong SCHEMBL30286004 | 0.78 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| Ammonia Solution, Strong SCHEMBL4411335 | 0.78 | GSK3B (0.38) | BCHEGSK3BKMT2A | |
| SCHEMBL28691443 | 0.72 | GSK3B (0.37) | GSK3BKMT2A | |
| SCHEMBL11779546 | 0.66 | CA12 (0.36) | BCHEKMT2A | |
| SCHEMBL21647910 | 0.62 | BCHE (0.37) | BCHEGSK3B | |
| SCHEMBL3326021 | 0.61 | MEN1 (0.42) | BCHEGSK3BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998740-B1 | METHOD FOR PREDICTING CLINICAL EFFECT OF IMMUNOTHERAPY | INT INST CANCER IMMUNOLOGY INC (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-10408840-B2 | Method for predicting clinical effect of immunotherapy | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-9851356-B2 | Method for measuring anti-WT1 antibody | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20170138958-A1 | METHOD FOR MEASURING ANTI-WT1 ANTIBODY | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2017-05-18 | — | — | US | disclosed |
| US-20160084841-A1 | Method for Predicting Clinical Effect of Immunotherapy | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2016-03-24 | — | — | US | disclosed |
| EP-2998740-A1 | METHOD FOR PREDICTING CLINICAL EFFECT OF IMMUNOTHERAPY | International Institute of Cancer Immunology, Inc. (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-20140227799-A1 | METHOD FOR MEASURING ANTI-WT1 ANTIBODY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2757373-A1 | METHOD FOR MEASURING ANTI-WT1 ANTIBODY | International Institute of Cancer Immunology, Inc. (JP) | 2014-07-23 | — | — | EP | disclosed |