Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3860163 | 1.00 | GSK3B (0.38) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL30286004 | 1.00 | GSK3B (0.38) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28099769 | 1.00 | GSK3B (0.38) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL29366806 | 0.98 | GSK3B (0.38) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL378842 | 0.98 | GSK3B (0.38) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL15876008 | 0.78 | AVPR2 (0.31) | GSK3BBCHEKMT2A | |
| SCHEMBL21647910 | 0.77 | BCHE (0.37) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL3952904 | 0.77 | CRHBP (0.35) | — | |
| SCHEMBL10481670 | 0.75 | — | — | |
| SCHEMBL8342783 | 0.73 | ALDH1A1 (0.35) | GSK3BBCHEPPARGALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585110-A1 | ANTIBODIES TO THE C3D FRAGMENT OF COMPLEMENT COMPONENT 3 | The Regents of the University of Colorado, A Body Corporate (US) | 2013-05-01 | — | — | EP | disclosed |
| US-7863007-B2 | Marker for prolonged rupture of membranes | SWISS ASIAN PROPERTY LIMITED (HK) | 2011-01-04 | — | — | US | disclosed |
| US-20090068692-A1 | MARKER FOR PROLONGED RUPTURE OF MEMBRANES | SWISS ASIAN PROPERTY LIMITED (HK) | 2009-03-12 | — | — | US | disclosed |
| EP-1937709-A1 | A MARKER FOR PROLONGED RUPTURE OF MEMBRANES | Bio Source (Wuhan) Technology Ltd. (CN) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007030890-A1 | A MARKER FOR PROLONGED RUPTURE OF MEMBRANES | BIO SOURCE (WUHAN) TECHNOLOGY LTD (CN) | 2007-03-22 | — | — | WO | disclosed |
| WO-2003018634-A1 | MONOCLONAL ANTIBODY CB874 DIRECTED TO AN UNKNOWN ANTIGEN FROM UMBILICAL CORD BLOOD | VOROTELIAK VICTOR (AU) | 2003-03-06 | — | — | WO | disclosed |
| EP-0689552-B1 | A METHOD OF DETECTING RUPTURE OF THE AMNIOTIC MEMBRANES IN PREGANT MAMMALS | VOROTELIAK VICTOR (AU) | 2002-10-30 | — | — | EP | disclosed |
| WO-2002064633-A1 | MONOCLONAL ANTIBODY AGAINST AN UNKNOWN ANTIGEN FROM AMNIOTIC FLU ID AND ITS METHOD OF PREPARATION | VOROTELIAK VICTOR (AU) | 2002-08-22 | — | — | WO | disclosed |
| US-5783396-A | ANTIGEN LOCATED IN AMNIOTIC FLUID HAVING SPECIFIED PHYSICAL PROPERTIES; USED TO PRODUCE ANTIBODY AGAINST AMNIOTIC FLUID FOR IMMUNOASSAY | VOROTELIAK VICTOR (AU) | 1998-07-21 | — | — | US | disclosed |
| EP-0689552-A4 | A METHOD OF DETECTING RUPTURE OF THE AMNIOTIC MEMBRANES IN PREGANT MAMMALS | VOROTELIAK VICTOR (AU) | 1997-07-02 | — | — | EP | disclosed |
| EP-0689552-A1 | A METHOD OF DETECTING RUPTURE OF THE AMNIOTIC MEMBRANES IN PREGANT MAMMALS | VOROTELIAK, Victor (AU) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021687-A1 | A METHOD OF DETECTING RUPTURE OF THE AMNIOTIC MEMBRANES IN PREGANT MAMMALS | VOROTELIAK VICTOR (AU) | 1994-09-29 | — | — | WO | disclosed |