Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.52 |
| ▸ | ITGAV | P06756 | 6/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 9/20 | 0.40 |
| ▸ | MC5R | P33032 | 9/20 | 0.40 |
| ▸ | MC3R | P41968 | 9/20 | 0.40 |
| ▸ | MC1R | Q01726 | 9/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15876018 | 0.95 | ITGB3 (0.45) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL15397365 | 0.81 | ITGB3 (0.59) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL10138562 | 0.81 | ITGB3 (0.59) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL12463308 | 0.80 | ITGB3 (0.57) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL24872452 | 0.79 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL7743670 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL22970321 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL7744260 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL19981446 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL15888949 | 0.78 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGA5KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2757098-A1 | Compounds for Functionalizing Biomaterials | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2014-07-23 | — | — | EP | disclosed |