SCHEMBL15877263

SCHEMBL15877263

C=C(C)C(=O)OCCc1ccc(-c2ccc(-c3cccs3)s2)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.50
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 5/20 0.46
LMNA P02545 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
MAPT P10636 1/20 0.46
LTA4H P09960 1/20 0.44
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
HPGD P15428 3/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 2/20 0.39
HSD17B10 Q99714 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9075962 0.81 MAPT (0.47) ALDH1A1KDM4EL3MBTL1MAPTNPC1
SCHEMBL13419960 0.79 TSHR (0.50) ALDH1A1LMNANPC1HPGDPOLB
SCHEMBL498734 0.76 DPP4 (0.66) DPP4ALDH1A1KDM4ELMNAL3MBTL1
SCHEMBL13407318 0.73 TSHR (0.43) ALDH1A1LMNANPC1HPGDPOLB
SCHEMBL13857533 0.72 DPP4 (0.53) DPP4ALDH1A1KDM4ELMNAL3MBTL1
SCHEMBL17921103 0.72 DPP4 (0.50) DPP4ALDH1A1KDM4ELMNAL3MBTL1
SCHEMBL799502 0.72 DPP4 (0.52) DPP4ALDH1A1KDM4ELMNAL3MBTL1
SCHEMBL13419928 0.72 TSHR (0.48) DPP4ALDH1A1LMNAPOLBHTT
SCHEMBL4853338 0.72 DPP4 (0.64) DPP4ALDH1A1KDM4ELMNAL3MBTL1
SCHEMBL499162 0.72 DPP4 (0.74) DPP4ALDH1A1KDM4ELMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725544-B2 Preparation of conjugated aromatic/heteroaromatic oligomer-containing dielectric polymers and their applications UNIVERSITY OF SOUTH CAROLINA (US) 2017-08-08 US disclosed
US-9725544-B2 Preparation of conjugated aromatic/heteroaromatic oligomer-containing dielectric polymers and their applications UNIVERSITY OF SOUTH CAROLINA (US) 2017-08-08 US disclosed
US-20160264702-A1 PREPARATION OF CONJUGATED AROMATIC/HETEROAROMATIC OLIGOMER-CONTAINING DIELECTRIC POLYMERS AND THEIR APPLICATIONS UNIVERSITY OF SOUTH CAROLINA 2016-09-15 US disclosed
US-9346906-B2 Preparation of conjugated aromatic/heteroaromatic oligomer-containing dielectric polymers and their applications UNIVERSITY OF SOUTH CAROLINA (US) 2016-05-24 US disclosed
US-20140206821-A1 Preparation of Conjugated Aromatic/Heteroaromatic Oligomer-Containing Dielectric Polymers and Their Applications NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2014-07-24 US disclosed