SCHEMBL9075962

SCHEMBL9075962

C=C(C)C(=O)OCCc1cccs1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP2C19 P33261 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28093241 0.88 NPC1 (0.56) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL28093005 0.88 NPC1 (0.56) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL28050476 0.88 NPC1 (0.56) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL28093240 0.88 NPC1 (0.56) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL25918565 0.86 TSHR (0.52) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL8295298 0.84 NPC1 (0.51) CYP2C19MEN1CYP3A4HPGDKMT2A
SCHEMBL3070804 0.83 SMN1; SMN2 (0.50) MAPTTDP1CYP2C19KDM4EMEN1
SCHEMBL15877263 0.81 DPP4 (0.50) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL11878300 0.80 ALDH1A1 (0.45) TDP1MEN1HPGDKMT2ASMN1; SMN2
SCHEMBL432741 0.80 KMT2A (0.58) MAPTMEN1HPGDKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406738-A Pressure sensitive adhesive composition 株式会社LG化学 2017-11-28 CN claimed
CN-101932667-B Acrylic pressure-sensitive adhesive comprising optically anisotropic compound, polarizing plate and liquid crystal display including the same LG CHEMICAL LTD 2013-08-21 CN claimed
US-20210393481-A1 SYSTEMS AND METHODS FOR PRESERVATIVE REMOVAL FROM OPHTHALMIC FORMULATIONS COMPRISING COMPLEXING AGENTS TearClear Corp. 2021-12-23 US disclosed
EP-3920988-A1 SYSTEMS AND METHODS FOR PRESERVATIVE REMOVAL FROM OPHTHALMIC FORMULATIONS COMPRISING COMPLEXING AGENTS Tearclear Corp. (US) 2021-12-15 EP disclosed
WO-2020163528-A1 SYSTEMS AND METHODS FOR PRESERVATIVE REMOVAL FROM OPHTHALMIC FORMULATIONS COMPRISING COMPLEXING AGENTS TearClear Corp. (US) 2020-08-13 WO disclosed
US-20200246222-A1 Systems and Methods for Preservative Removal from Ophthalmic Formulations Comprising Complexing Agents TearClear Corp. 2020-08-06 US disclosed
CN-110262188-A Green photonasty resin composition, colored filter and image display device 东友精细化工有限公司 2019-09-20 CN disclosed
CN-110114724-A Photopolymer composition 株式会社LG化学 2019-08-09 CN disclosed
CN-105792860-B Reflective soft acrylic material with high refractive index and minimum 诺华股份有限公司 2019-06-04 CN disclosed
CN-109790235-A PHOTOPOLYMER COMPOSITION 株式会社LG化学 2019-05-21 CN disclosed
CN-107406738-A Pressure sensitive adhesive composition 株式会社LG化学 2017-11-28 CN disclosed
CN-101932667-B Acrylic pressure-sensitive adhesive comprising optically anisotropic compound, polarizing plate and liquid crystal display including the same LG CHEMICAL LTD 2013-08-21 CN disclosed
EP-0273710-B2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin NIPPON CATALYTIC CHEM IND (JP) 1996-10-16 EP disclosed
EP-0358524-B1 Optical material composed of resin having high refractive index NIPPON CATALYTIC CHEM IND (JP) 1994-06-01 EP disclosed
US-5132384-A Acrylated polyether copolymer NIPPON SHOKUBAI CO., LTD. (JP) 1992-07-21 US disclosed
EP-0430073-A2 Optical material of low specific gravity and excellent impact resistance, optical molding product using the optical material and manufacturing method thereof NIPPON SHOKUBAI CO., LTD. (JP) 1991-06-05 EP disclosed
US-4973640-A COPOLYMER OF DIACRYLATE MONOMER AND STYRENE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-11-27 US disclosed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US disclosed
EP-0358524-A2 Optical material composed of resin having high refractive index NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1990-03-14 EP disclosed
EP-0273710-A2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246222-A1 Systems and Methods for Preservative Removal from Ophthalmic Formulations Comprising Complexing Agents SMURF1, CRYAA, PON1 MAPT 274/4885TDP1 2279/4885CYP2C19 3077/4885
US-20210393481-A1 SYSTEMS AND METHODS FOR PRESERVATIVE REMOVAL FROM OPHTHALMIC FORMULATIONS COMPRISING COMPLEXING AGENTS SMURF1, CRYAA, PON1 MAPT 274/4885TDP1 2279/4885CYP2C19 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.