Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635219 | 1.00 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL2377572 | 0.81 | POLB (0.67) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL14635548 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL15879018 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL11126118 | 0.79 | ALDH1A1 (0.65) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL11219399 | 0.79 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9180266 | 0.77 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL14635604 | 0.77 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL10478322 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL12532944 | 0.74 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303001-B2 | Intermediate of statin drugs and preparation thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-04-05 | — | — | US | disclosed |
| US-20140206883-A1 | INTERMEDIATE OF STATIN DRUGS AND PREPARATION THEREOF | YICHANG CHANGJIANG PHARMACEUTICAL CO., LTD. (CN) | 2014-07-24 | — | — | US | disclosed |
| CN-103649068-A | Statin drug intermediate and preparation method thereof | GUANGDONG HEC PHARMACEUTICAL | 2014-03-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206883-A1 | INTERMEDIATE OF STATIN DRUGS AND PREPARATION THEREOF | HMGCR, SULT1E1, CYP3A5 | ALDH1A1 307/4885POLB 2567/4885MAPT 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.