Hinokitiol

Hinokitiol

SCHEMBL158795

CC(C)c1cccc(=O)c(O)c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.71
HDAC4 P56524 3/20 0.71
HDAC8 Q9BY41 3/20 0.71
ALOX12 P18054 3/20 0.71
TP53 P04637 2/20 0.71
HDAC2 Q92769 2/20 0.71
ALDH1A1 P00352 2/20 0.71
HTT P42858 2/20 0.71
CA2 P00918 2/20 0.71
KDM4E B2RXH2 1/20 0.71
MDM4 O15151 1/20 0.71
CA1 P00915 1/20 0.71
CYP3A4 P08684 1/20 0.71
MAPT P10636 1/20 0.71
HPGD P15428 1/20 0.71
ALOX15 P16050 1/20 0.71
CA5A P35218 1/20 0.71
MDM2 Q00987 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
CA9 Q16790 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hinokitiol SCHEMBL27551974 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27476854 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495431 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27551973 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27478967 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495432 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27478148 0.98 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27478147 0.93 TYR (0.62) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495430 0.93 HDAC4 (0.62) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL4653999 0.87 TP53 (0.70) TYRHDAC4HDAC8ALOX12TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3153 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4319884-B1 COSMETIC COMPOSITION COMPRISING HINOKITIOL UNILEVER IP HOLDINGS B V (NL) 2026-05-27 EP claimed
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
CN-122031314-A Mineral component extracted from Baoning slurry, extraction method thereof and cosmetic composition containing Baoning slurry mineral extract 碧珂丝株式会社 2026-05-15 CN claimed
US-20260124200-A1 METHOD OF TREATING NEURODEGENERATIVE DISEASES UNIV ILLINOIS (US) 2026-05-07 US claimed
EP-4735567-A1 BIODEGRADABLE CHELATING AGENTS AND METHODS FOR FABRIC CARE The Procter & Gamble Company (US) 2026-05-06 EP claimed
EP-4734945-A1 WASH COMPOSITION WITH ANIONIC SULFATE AND SULTAINE NOT RELIANT ON PALM KERNEL OIL Unilever IP Holdings B.V. (NL) 2026-05-06 EP claimed
EP-4735568-A1 BIODEGRADABLE CHELATING AGENTS AND METHODS FOR FABRIC CARE The Procter & Gamble Company (US) 2026-05-06 EP claimed
EP-4734933-A1 COSMETIC COMPOSITION Unilever IP Holdings B.V. (NL) 2026-05-06 EP claimed
EP-4734970-A1 COMPOSITION COMPRISING HINOKITIOL AND ZINC SALT FOR USE IN THE TREATMENT OF HERPES LABIALIS AAA Investments B.V. (NL) 2026-05-06 EP claimed
EP-1441691-A2 BETA-GLUCURONIDASE INHIBITORS FOR USE IN DEODORANTS AND ANTIPERSPIRANTS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-08-04 EP claimed
WO-2004012692-A1 ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS WARNER-LAMBERT COMPANY LLC (US) 2004-02-12 WO claimed
US-20040018154-A1 ORAL CARE COMPOSITIONS COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS AND METHODS OF USING THE SAME MCNEIL-PPC, INC 2004-01-29 US claimed
WO-2003039505-A2 ss-GLUCURONIDASE INHIBITORS FOR USE IN DEODORANTS AND ANTIPERSPIRANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-05-15 WO claimed
US-20020098211-A1 ANTIMICROBIAL AGENT AND USES THEREOF, IN PARTICULAR IN COSMETICS AND DERMATOLOGY L'OREAL (FR) 2002-07-25 US claimed
EP-1000542-B1 Antimicrobial composition and its use, especially in cosmetics and dermatology OREAL (FR) 2002-06-12 EP claimed
US-5877210-A CONTROLLING IMMUNE RESPONSE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-02 US claimed
CN-1189099-A Antibacterial, bactericidal and antiseptic agent, dermatological preparation and detergent composition P AND PF CO LTD (JP) 1998-07-29 CN claimed
US-5565491-A FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US claimed
US-4361581-A ANTI-SUNTAN TROPOLONES Fukuda, Yasuaki (JP) 1982-11-30 US claimed