Hinokitiol

Hinokitiol

SCHEMBL27478147

CC(C)c1cccc(=O)c(O)c1.O=[Ti]=O.[AlH3]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.62
HDAC4 P56524 3/20 0.62
HDAC8 Q9BY41 3/20 0.62
ALOX12 P18054 3/20 0.62
TP53 P04637 2/20 0.62
HDAC2 Q92769 2/20 0.62
ALDH1A1 P00352 2/20 0.62
HTT P42858 2/20 0.62
CA2 P00918 2/20 0.62
KDM4E B2RXH2 1/20 0.62
MDM4 O15151 1/20 0.62
CA1 P00915 1/20 0.62
CYP3A4 P08684 1/20 0.62
MAPT P10636 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
CA5A P35218 1/20 0.62
MDM2 Q00987 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CA9 Q16790 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hinokitiol SCHEMBL27476854 0.94 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL158795 0.93 TYR (0.71) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27551974 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495432 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27478967 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495431 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27478148 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27551973 0.91 TYR (0.69) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL27495430 0.86 HDAC4 (0.62) TYRHDAC4HDAC8ALOX12TP53
Hinokitiol SCHEMBL4653999 0.80 TP53 (0.70) TYRHDAC4HDAC8ALOX12TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1189099-A Antibacterial, bactericidal and antiseptic agent, dermatological preparation and detergent composition P AND PF CO LTD (JP) 1998-07-29 CN disclosed