SCHEMBL15880425

SCHEMBL15880425

Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1O

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 14/20 0.64
PTGER3 P43115 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL252003 0.85 PTGER1 (0.51) PTGER1
SCHEMBL14289878 0.82 PTGER1 (0.61) PTGER1PTGER3
SCHEMBL14289930 0.81 PTGER1 (0.60) PTGER1PTGER3
SCHEMBL14969642 0.80 HIF1A (0.45) PTGER1
SCHEMBL4683984 0.79 PTGER1 (0.85) PTGER1
SCHEMBL4090618 0.79 PTGER1 (0.82) PTGER1
SCHEMBL3176376 0.78 SLC22A12 (0.59) PTGER1
SCHEMBL14289965 0.78 PTGER1 (0.72) PTGER1
SCHEMBL4091313 0.78 PTGER1 (0.85) PTGER1
SCHEMBL4684656 0.78 PTGER1 (1.00) PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2945932-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2015-11-25 EP disclosed
WO-2014113814-A1 COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE ALLERGAN, INC. (US) 2014-07-24 WO disclosed