Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178992 | 0.87 | SLC22A12 (0.53) | SLC22A12PTGER1KEAP1NFE2L2 | |
| SCHEMBL6405032 | 0.83 | SLC22A12 (0.54) | SLC22A12KEAP1NFE2L2 | |
| SCHEMBL15880425 | 0.78 | PTGER1 (0.64) | PTGER1 | |
| SCHEMBL3176760 | 0.76 | PTGER1 (0.48) | SLC22A12PTGER1 | |
| Hydrochloric Acid SCHEMBL3178760 | 0.75 | PTGER1 (0.49) | SLC22A12PTGER1 | |
| SCHEMBL11977238 | 0.74 | SLC22A12 (1.00) | SLC22A12KEAP1NFE2L2 | |
| SCHEMBL11976699 | 0.74 | SLC22A12 (1.00) | SLC22A12KEAP1NFE2L2 | |
| SCHEMBL14289878 | 0.74 | PTGER1 (0.61) | PTGER1 | |
| SCHEMBL14289930 | 0.73 | PTGER1 (0.60) | PTGER1 | |
| SCHEMBL14289965 | 0.73 | PTGER1 (0.72) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022486-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022486-A1 | COMPOUNDS | SCD, CYP11B2, SCD5 | SLC22A12 1443/4885PTGER1 681/4885KEAP1 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.