SCHEMBL1588053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27537638	0.88	ALDH1A1 (0.53)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL28322738	0.87	ALDH1A1 (0.62)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL1587371	0.82	ALDH1A1 (0.50)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL276955	0.81	ALDH1A1 (0.58)	ALDH1A1KDM4EMAPTPOLBLMNA
	SCHEMBL1588116	0.79	HPGD (0.51)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL276231	0.78	ALDH1A1 (0.46)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL4148614	0.77	ALDH1A1 (0.55)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL19316038	0.76	HDAC6 (0.56)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL1587423	0.76	ALDH1A1 (0.54)	ALDH1A1RAB9AKDM4ENPC1MAPT
	SCHEMBL12265915	0.75	ALDH1A1 (0.50)	ALDH1A1RAB9AKDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.