SCHEMBL1589

SCHEMBL1589

O=C(O)C=C(O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533836 1.00
SCHEMBL1588 1.00
SCHEMBL28169695 1.00 TSHR (0.41)
SCHEMBL10339835 0.96 TSHR (0.39)
SCHEMBL2277005 0.93 TSHR (0.38)
SCHEMBL2276994 0.93 TSHR (0.38)
Malonic Acid SCHEMBL7483423 0.85 KDM4E (0.56)
Glycolic Acid SCHEMBL26664846 0.85 KDM4E (0.44)
Malonic Acid SCHEMBL7483448 0.85 KDM4E (0.56)
SCHEMBL19386132 0.81 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21249 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120754262-B Nucleic acid delivery vector and preparation method and application thereof Shenzhen Jinlin Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-20260124270-A1 ISOCYCLOSPORIN A FOR TOPICAL TREATMENT OF OCULAR DISEASES DOMPE FARM SPA (IT) 2026-05-07 US claimed
US-20260109671-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS INC (US) 2026-04-23 US claimed
EP-4105213-B1 PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND THERAPEUTIC PHARMACEUTIC COMPOSITION COMPRISING SAME PHAROS IBIO CO LTD (KR) 2026-04-15 EP claimed
US-20260070913-A1 7-AMINO-3,4-DIHYDROPYRIMIDOPYRIMIDIN-2-ONE DERIVATIVE HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME KOREA INST SCI & TECH (KR) 2026-03-12 US claimed
US-20260070903-A1 NOVEL PYRIDO[3,4-D]PYRIMIDIN-8-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING CANCER, COMPRISING SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-12 US claimed
US-12558399-B2 Isocyclosporin A for topical treatment of ocular diseases DOMPE' FARMACEUTICI S.P.A. (IT) 2026-02-24 US claimed
US-20250387367-A1 METHODS AND COMPOSITIONS RELATING TO INHIBITION OF ALDEHYDE DEHYDROGENASES FOR TREATMENT OF CANCER PENN STATE RES FOUND (US) 2025-12-25 US claimed
US-20250367173-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME LIGACHEM BIOSCIENCES INC (KR) 2025-12-04 US claimed
US-12466812-B2 Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-11 US claimed
US-5488095-A DETERGENT AND CLEANER ADDITIVES BASF AKTIENGESELLSCHAFT (DE) 1996-01-30 US claimed
US-5225528-A Controlling premature labor MERCK & CO., INC. (US) 1993-07-06 US claimed
EP-0444898-A1 Cyclic hexapeptide oxytocin antagonists MERCK & CO. INC. (US) 1991-09-04 EP claimed
EP-0435505-A2 Polymers and detergent compositions containing them UNILEVER PLC (GB) 1991-07-03 EP claimed
EP-0227623-B1 USE OF ALKYLAMINE SALTS AS VISCOSITY REGULATING SUBSTANCE KEMIRA KEMI AKTIEBOLAG (SE) 1990-08-01 EP claimed
EP-0190587-A1 Soluble quinazolino-1,4-benzodiazepin-5,13-dione derivatives, process for their preparation and pharmaceutical composition containing them MERCK & CO. INC. (US) 1986-08-13 EP claimed
US-4559338-A Soluble quinazolino-1,4-benzodiazepin-5,13-dione derivatives MERCK & CO., INC. (US) 1985-12-17 US claimed
US-4156701-A CHEMICAL INTERMEDIATE FOR CYSTEINE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-29 US claimed
US-4048130-A COPOLYMERIZATION, UNSATURATED ACIDS LONZA LTD. (CH) 1977-09-13 US claimed
US-3966749-A Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof INTERX RESEARCH CORPORATION (US) 1976-06-29 US claimed