Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL7483423 | 1.00 | KDM4E (0.56) | KDM4ETSHRLDHASRRALOX15 | |
| SCHEMBL28169695 | 0.85 | TSHR (0.41) | KDM4ETSHR | |
| SCHEMBL1588 | 0.85 | — | — | |
| SCHEMBL1533836 | 0.85 | — | — | |
| SCHEMBL1589 | 0.85 | — | — | |
| Glycolic Acid SCHEMBL26664846 | 0.83 | KDM4E (0.44) | KDM4ETSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL10339835 | 0.82 | TSHR (0.39) | KDM4ETSHR | |
| SCHEMBL2277005 | 0.79 | TSHR (0.38) | KDM4ETSHR | |
| SCHEMBL2276994 | 0.79 | TSHR (0.38) | KDM4ETSHR | |
| Aconitic Acid SCHEMBL22334 | 0.72 | TSHR (1.00) | KDM4ETSHRLDHASRRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230220-A1 | BETA-AMINOACID COMPOUNDS USEFUL FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELI LILLY AND COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034571-A1 | β-AMINOACID COMPOUNDS USEFUL FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |