Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15890939 | 0.99 | S1PR1 (0.53) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| Trifluoroacetic Acid SCHEMBL950977 | 0.93 | S1PR1 (0.46) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| SCHEMBL15890873 | 0.93 | S1PR1 (0.62) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| Trifluoroacetic Acid SCHEMBL947890 | 0.92 | S1PR1 (0.47) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| SCHEMBL15890859 | 0.91 | S1PR1 (0.64) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| SCHEMBL15890862 | 0.89 | PARP10 (0.52) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| SCHEMBL15890973 | 0.88 | S1PR1 (0.56) | S1PR1S1PR3S1PR5FFAR1LTA4H | |
| SCHEMBL15890978 | 0.87 | PARP15 (0.51) | S1PR1S1PR3PARP15PARP10S1PR5 | |
| SCHEMBL15890853 | 0.87 | S1PR1 (0.58) | S1PR1S1PR3S1PR5FFAR1LTA4H | |
| SCHEMBL3059752 | 0.87 | THRA (0.61) | PARP15PARP10THRATHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791159-B2 | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | claimed |