Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.70 |
| ▸ | MMP2 | P08253 | 11/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158952 | 1.00 | MMP9 (0.70) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL10585071 | 0.96 | MMP9 (0.76) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL8001084 | 0.96 | MMP9 (0.76) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL457772 | 0.96 | MMP9 (0.76) | MMP9MMP2TDP1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9087107 | 0.95 | MMP9 (0.74) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL8322406 | 0.92 | MMP9 (0.71) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL232590 | 0.91 | MMP9 (0.70) | MMP9MMP2TDP1ITGB3ITGA2B | |
| SCHEMBL796113 | 0.91 | MMP9 (0.70) | MMP9MMP2TDP1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL14059216 | 0.90 | MMP9 (0.68) | MMP9MMP2TDP1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL28895937 | 0.90 | MMP9 (0.68) | MMP9MMP2TDP1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031118-A2 | CELL PERMEABLE INHIBITORS OF ANAPHASE PROMOTING COMPLEX | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-08 | — | — | WO | disclosed |