Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17697641 | 0.84 | PDCD1 (0.52) | DPP4DPP8PDCD1CD274BRD4 | |
| Ethylene Glycol SCHEMBL23466901 | 0.80 | TSHR (0.47) | PDCD1CD274TSHRACHENPC1 | |
| SCHEMBL3858794 | 0.77 | PDCD1 (0.53) | DPP4PDCD1CD274TSHRACHE | |
| SCHEMBL29876578 | 0.77 | TSHR (0.56) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL2222213 | 0.77 | TSHR (0.56) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL30169568 | 0.77 | ACHE (0.64) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL197690 | 0.77 | ACHE (0.64) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL30354037 | 0.77 | ACHE (0.64) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL10088552 | 0.77 | PPARG (0.44) | PDCD1CD274TSHRPPARGPPARA | |
| SCHEMBL1589935 | 0.75 | KDM4E (0.50) | SMN1; SMN2PPARGPPARAHPGDMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276723-B1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-27 | — | — | EP | disclosed |
| CN-102026958-B | Compounds for electronic devices | MERCK PATENT GMBH | 2014-08-20 | — | — | CN | disclosed |
| US-8766001-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8766001-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8766001-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |
| WO-2009141026-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH, (DE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092701-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | SLCO4C1, SLCO2A1, TOE1 | DPP4 3937/4885DPP8 4201/4885PDCD1 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.