Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 18/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894478 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL7926073 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL1391475 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL16709745 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1LMNAKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1391474 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL27203069 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL7925290 | 0.82 | XDH (0.54) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL558695 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL1391619 | 0.81 | XDH (0.53) | KDM4EALDH1A1LMNAKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL1391618 | 0.81 | XDH (0.53) | KDM4EALDH1A1LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140205846-A1 | MULTI-DIMENSIONAL NETWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140205846-A1 | MULTI-DIMENSIONAL NETWORKS | DCX, CCNB2, CCNA2 | KDM4E 3930/4885ALDH1A1 1594/4885LMNA 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.