SCHEMBL15898543

SCHEMBL15898543

COC(=O)c1ccc(C(=O)OC)c(NC(=O)CN)c1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 15/20 0.70
KDM4E B2RXH2 14/20 0.70
HPGD P15428 5/20 0.70
HSD17B10 Q99714 3/20 0.70
MAPT P10636 3/20 0.68
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
TSHR P16473 2/20 0.61
DNMT1 P26358 1/20 0.61
LMNA P02545 3/20 0.60
GAA P10253 2/20 0.59
GLA P06280 1/20 0.59
HTT P42858 1/20 0.58
PKM P14618 1/20 0.58
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933609 0.85 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL14513124 0.84 ALDH1A1 (0.77) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL16702278 0.84 KMT2A (0.51) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL15894475 0.83 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL558695 0.83 KDM4E (0.68) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL14338571 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL13265935 0.81 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL14413343 0.81 KDM4E (0.69) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL13088436 0.81 KDM4E (0.69) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL30487008 0.81 KDM4E (0.69) ALDH1A1KDM4EHPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140205846-A1 MULTI-DIMENSIONAL NETWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140205846-A1 MULTI-DIMENSIONAL NETWORKS DCX, CCNB2, CCNA2 ALDH1A1 1594/4885KDM4E 3930/4885HPGD 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.