SCHEMBL15899232

SCHEMBL15899232

COCCC(C)(OC(=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KCNN4 O15554 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.38
CES1 P23141 1/20 0.38
POLB P06746 3/20 0.37
CHRM3 P20309 2/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
HPGD P15428 2/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899483 0.90 KDM4E (0.45) CYP2C19HIF1AKDM4EALDH1A1LMNA
SCHEMBL15899376 0.84 CYP2C19 (0.42) CYP2C19HIF1AKDM4EALDH1A1LMNA
SCHEMBL984518 0.83 CYP2C19 (0.47) CYP2C19HIF1AKDM4EALDH1A1LMNA
SCHEMBL15899347 0.83 CYP2C19 (0.41) CYP2C19HIF1AKDM4EALDH1A1LMNA
SCHEMBL15899541 0.83 CYP2C19 (0.41) CYP2C19HIF1AKDM4EALDH1A1LMNA
SCHEMBL15899174 0.81 L3MBTL1 (0.44) CYP2C19HIF1AALDH1A1SMN1; SMN2KMT2A
SCHEMBL15899171 0.79 KDM4E (0.40) CYP2C19HIF1AKDM4EALDH1A1SMN1; SMN2
SCHEMBL7949342 0.79 CYP2C19 (0.50) CYP2C19HIF1AALDH1A1KCNN4KMT2A
SCHEMBL15899391 0.78 SMN1; SMN2 (0.40) CYP2C19HIF1AALDH1A1SMN1; SMN2TSHR
SCHEMBL28615506 0.77 CYP2C19 (0.48) CYP2C19HIF1AALDH1A1SMN1; SMN2KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759552-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2016-02-10 EP disclosed
US-9243081-B2 Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2016-01-26 US disclosed
US-20140343237-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-11-20 US disclosed
EP-2759552-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-07-30 EP disclosed