Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937954 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1HTR1ATHPOBLM | |
| SCHEMBL10879127 | 0.91 | APAF1 (0.62) | KDM4EALDH1A1HTR1ASMN1; SMN2APAF1 | |
| SCHEMBL14943968 | 0.91 | APAF1 (0.62) | KDM4EALDH1A1HTR1ASMN1; SMN2APAF1 | |
| SCHEMBL10879125 | 0.91 | APAF1 (0.62) | KDM4EALDH1A1HTR1ASMN1; SMN2APAF1 | |
| SCHEMBL2290305 | 0.85 | APAF1 (0.57) | KDM4EHIF1AADRB2APAF1L3MBTL1 | |
| SCHEMBL20261941 | 0.85 | ANPEP (0.55) | KDM4EADRB2APAF1L3MBTL1MEN1 | |
| SCHEMBL2296647 | 0.85 | APAF1 (0.53) | KDM4EALDH1A1SMN1; SMN2APAF1L3MBTL1 | |
| SCHEMBL82474 | 0.85 | APAF1 (0.53) | KDM4EALDH1A1SMN1; SMN2APAF1L3MBTL1 | |
| SCHEMBL2295948 | 0.85 | APAF1 (0.53) | KDM4EALDH1A1SMN1; SMN2APAF1L3MBTL1 | |
| SCHEMBL2298353 | 0.85 | APAF1 (0.53) | KDM4EALDH1A1CYP2C9APAF1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759540-A2 | Beta-3 receptor ligands and their use in therapy | Universita' Degli Studi di Bari (IT) | 2014-07-30 | — | — | EP | disclosed |