Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 17/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL17313119 | 0.91 | ACHE (1.00) | ACHE | |
| SCHEMBL17320362 | 0.90 | ACHE (1.00) | ACHE | |
| Bromide SCHEMBL6751898 | 0.83 | ACHE (0.81) | ACHE | |
| Bromide SCHEMBL17313333 | 0.82 | ACHE (1.00) | ACHE | |
| Bromide SCHEMBL17313271 | 0.81 | ACHE (1.00) | ACHE | |
| Bromide SCHEMBL17313104 | 0.80 | ACHE (1.00) | ACHE | |
| Bromide SCHEMBL6752633 | 0.80 | ACHE (0.78) | ACHE | |
| SCHEMBL17321128 | 0.80 | ACHE (0.80) | ACHE | |
| SCHEMBL17320352 | 0.79 | ACHE (0.82) | ACHE | |
| SCHEMBL17321076 | 0.79 | ACHE (1.00) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759536-A1 | Oxidisable pyridine derivatives, their preparation and use as anti-Alzheimer agents | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2014-07-30 | — | — | EP | disclosed |