Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL11969678 | 0.93 | PDE10A (0.87) | PDE10ASLC6A3 | |
| SCHEMBL1758603 | 0.91 | PDE10A (0.84) | PDE10ASLC6A3 | |
| SCHEMBL15899657 | 0.87 | PDE10A (0.78) | PDE10ASLC6A3 | |
| SCHEMBL1759053 | 0.86 | PDE10A (0.75) | PDE10ASLC6A3 | |
| SCHEMBL1758722 | 0.83 | PDE10A (0.71) | PDE10ASLC6A3 | |
| Succinic Acid SCHEMBL11969523 | 0.81 | PDE10A (0.68) | PDE10ASLC6A3 | |
| SCHEMBL17088195 | 0.80 | SLC6A3 (0.69) | PDE10ASLC6A3 | |
| SCHEMBL17088197 | 0.80 | SLC6A3 (0.69) | PDE10ASLC6A3 | |
| SCHEMBL17089021 | 0.79 | SLC6A3 (0.67) | PDE10ASLC6A3 | |
| SCHEMBL15899669 | 0.79 | SLC6A3 (0.70) | PDE10ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493513-B1 | RADIOLABELLED PDE10 LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2014-07-30 | — | — | EP | claimed |
| US-20160058894-A1 | RADIOLABELED PDE10A LIGANDS | ABBVIE DEUTSCHLAND (DE) | 2016-03-03 | — | — | US | disclosed |
| US-20160058894-A1 | RADIOLABELED PDE10A LIGANDS | ABBVIE DEUTSCHLAND (DE) | 2016-03-03 | — | — | US | disclosed |
| US-9138494-B2 | Radiolabeled PDE10A ligands | ABBVIE INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9138494-B2 | Radiolabeled PDE10A ligands | ABBVIE INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2493513-B1 | RADIOLABELLED PDE10 LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2014-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058894-A1 | RADIOLABELED PDE10A LIGANDS | PDE10A, PDE3A, PDE5A | PDE10A 1/4885SLC6A3 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.