Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854062 | 0.93 | ALDH1A1 (0.74) | ALDH1A1LMNAKMT2AGAAKDM4E | |
| SCHEMBL23781727 | 0.88 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2AGAAF2 | |
| SCHEMBL17479215 | 0.87 | ALDH1A1 (0.78) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL925723 | 0.87 | ALDH1A1 (0.78) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL1710961 | 0.86 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL15575103 | 0.86 | ALDH1A1 (0.75) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL15575170 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL3653422 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL17479214 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL17479352 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937652-B1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | AVENTIS PHARMA INC (US) | 2014-07-30 | — | — | EP | claimed |