Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 13/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899990 | 0.89 | PIK3CD (0.42) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899894 | 0.88 | PIK3CD (0.44) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL15899980 | 0.85 | PIK3CD (0.37) | PIK3CDIDH1 | |
| SCHEMBL15899988 | 0.84 | PIK3CD (0.43) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899986 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3R2IDH1PIK3CG | |
| SCHEMBL15899979 | 0.82 | PIK3CD (0.42) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899996 | 0.81 | PIK3CD (0.41) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899829 | 0.81 | PIK3CD (0.41) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899984 | 0.80 | PIK3CD (0.46) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15900001 | 0.77 | PIK3CD (0.45) | PIK3CDPIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499129-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-07-30 | — | — | EP | claimed |