Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 14/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899998 | 0.89 | PIK3CD (0.41) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15900001 | 0.87 | PIK3CD (0.45) | PIK3CDPIK3R2 | |
| SCHEMBL15899988 | 0.87 | PIK3CD (0.43) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899986 | 0.85 | PIK3CD (0.46) | PIK3CDPIK3R2IDH1GPR6 | |
| SCHEMBL15899829 | 0.85 | PIK3CD (0.41) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899979 | 0.85 | PIK3CD (0.42) | PIK3CDPIK3R2IDH1GPR6 | |
| SCHEMBL15899996 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R2IDH1GPR6 | |
| SCHEMBL15899984 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899897 | 0.78 | HMOX1 (0.37) | PIK3CDPIK3R2IDH1 | |
| SCHEMBL15899894 | 0.77 | PIK3CD (0.44) | PIK3CDPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499129-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-07-30 | — | — | EP | claimed |