SCHEMBL15901702

SCHEMBL15901702

CCC(Cl)(CCN)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.44
SLC6A2 P23975 1/20 0.44
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
LOXL2 Q9Y4K0 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP2A6 P11509 1/20 0.39
HTR2A P28223 1/20 0.39
KIF11 P52732 7/20 0.39
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
RECQL P46063 1/20 0.37
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
MAOA P21397 1/20 0.35
AOC3 Q16853 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15901630 0.84 HTR2A (0.47) TAAR1SLC6A2LMNACYP2D6LOXL2
SCHEMBL6986193 0.76 TAAR1 (0.48) TAAR1SLC6A2LMNACYP2D6LOXL2
Hydrochloric Acid SCHEMBL27811778 0.74 TAAR1 (0.46) TAAR1SLC6A2LMNACYP2D6LOXL2
SCHEMBL28208675 0.73 SLC6A2 (0.42) TAAR1SLC6A2LMNACYP2D6SMN1; SMN2
Phosphine SCHEMBL11016680 0.73 SLC6A2 (0.48) TAAR1SLC6A2LMNACYP2D6LOXL2
SCHEMBL19840415 0.72 TAAR1 (0.56) TAAR1SLC6A2LMNACYP2D6LOXL2
SCHEMBL11833281 0.72
Benzylamine SCHEMBL28271374 0.71 LOXL2 (0.48) TAAR1CYP2D6LOXL2SMN1; SMN2KIF11
SCHEMBL5577579 0.71 TAAR1 (0.59) TAAR1SLC6A2LMNACYP2D6LOXL2
SCHEMBL22482651 0.71 TAAR1 (0.54) TAAR1SLC6A2LMNACYP2D6LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248064-B2 Conjugated diene polymer, conjugated diene polymer composition, and tire JAPAN ELASTOMER CO., LTD. (JP) 2022-02-15 US disclosed
CN-110167977-B Conjugated diene polymer, conjugated diene polymer composition, and tire 日本弹性体株式会社 2021-11-16 CN disclosed
CN-109476778-B Modified conjugated diene polymer, modified conjugated diene polymer composition, tire, and method for producing modified conjugated diene polymer 日本弹性体株式会社 2021-05-11 CN disclosed
EP-3581597-B1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND TIRE JAPAN ELASTOMER CO LTD (JP) 2021-05-05 EP disclosed
EP-3517552-B1 MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION, TIRE, AND METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER JAPAN ELASTOMER CO LTD (JP) 2020-11-11 EP disclosed
US-10822446-B2 Modified conjugated diene polymer, modified conjugated diene polymer composition, tire, and method for producing modified conjugated diene polymer JAPAN ELASTOMER CO., LTD. (JP) 2020-11-03 US disclosed
US-10766972-B2 Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-09-08 US disclosed
EP-3517552-A1 MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION, TIRE, AND METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER Japan Elastomer Co., Ltd. (JP) 2019-07-31 EP disclosed
EP-3260476-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2019-05-08 EP disclosed
US-20180037674-A1 Modified Conjugated Diene-Based Polymer and Method for Producing the Same, and Modified Conjugated Diene-Based Polymer Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-02-08 US disclosed
EP-3260476-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, MANUFACTURING METHOD THEREOF, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2017-12-27 EP disclosed
US-9085653-B2 Method for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, modified conjugated diene-based polymer composition, rubber composition and tire ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-07-21 US disclosed
EP-2754674-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION, RUBBER COMPOSITION, AND TIRE ASAHI KASEI CHEMICALS CORP (JP) 2015-03-11 EP disclosed
US-20140213721-A1 Method for Producing Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer Composition, Rubber Composition and Tire ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-07-31 US disclosed