Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15905075 | 0.92 | GAA (0.44) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905412 | 0.90 | ALDH1A1 (0.44) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905251 | 0.88 | RAD52 (0.43) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905069 | 0.85 | GAA (0.48) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905148 | 0.85 | MAPT (0.40) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905186 | 0.85 | KMT2A (0.53) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905427 | 0.84 | MAPT (0.41) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905397 | 0.84 | MAPT (0.44) | GAAALDH1A1MAPTLMNAP4HB | |
| SCHEMBL15905414 | 0.84 | MAPT (0.44) | GAAALDH1A1MAPTLMNAP4HB | |
| Hydrochloric Acid SCHEMBL17313819 | 0.84 | KMT2A (0.52) | GAAALDH1A1MAPTLMNAP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | claimed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |