Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904921 | 0.93 | MAPT (0.46) | TACR3CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL15904954 | 0.90 | MAPT (0.42) | TACR3CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL15905543 | 0.89 | TACR3 (0.48) | TACR3 | |
| SCHEMBL15905403 | 0.89 | MAPT (0.41) | TACR3CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL15905425 | 0.87 | MAPT (0.40) | TACR3CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL15905148 | 0.87 | MAPT (0.40) | TACR3CYP2C9CYP3A4MEN1KMT2A | |
| SCHEMBL15919629 | 0.87 | MMP2 (0.56) | TACR3ALDH1A1MAPTTDP1 | |
| SCHEMBL15905397 | 0.87 | MAPT (0.44) | CYP2C9CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL15905523 | 0.85 | MAPT (0.42) | CYP2C9CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL15905331 | 0.85 | FNTA (0.42) | CYP2C9CYP3A4ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | claimed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |