SCHEMBL15906206

SCHEMBL15906206

C[C@@H]1OC(CO)(CO)[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)[C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.31
SMYD2 Q9NRG4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14295864 0.86 MGAM (0.30) MGAM
SCHEMBL15906205 0.81
SCHEMBL701863 0.75 SLC28A1 (0.41)
SCHEMBL19179032 0.70 MGAM (0.30) MGAM
SCHEMBL10126291 0.69
SCHEMBL4546286 0.69
SCHEMBL25518968 0.69 CYP3A4 (0.36)
SCHEMBL9029247 0.68 SLC5A2 (0.43)
SCHEMBL9029257 0.68 SLC5A2 (0.43)
SCHEMBL10436007 0.68 SLC5A2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791083-B2 Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry ISIS PHARMACEUTICALS, INC. (US) 2014-07-29 US disclosed