Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 4/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029257 | 1.00 | SLC5A2 (0.43) | SLC5A2SLC5A1EPHX2L3MBTL1TYR | |
| SCHEMBL10436007 | 1.00 | SLC5A2 (0.43) | SLC5A2SLC5A1EPHX2L3MBTL1TYR | |
| SCHEMBL10767838 | 0.99 | SLC5A2 (0.45) | SLC5A2SLC5A1EPHX2L3MBTL1TYR | |
| SCHEMBL27933773 | 0.99 | SLC5A2 (0.45) | SLC5A2SLC5A1EPHX2L3MBTL1TYR | |
| SCHEMBL27777436 | 0.99 | SLC5A2 (0.45) | SLC5A2SLC5A1EPHX2L3MBTL1TYR | |
| SCHEMBL13765956 | 0.84 | OGA (0.36) | SLC5A2SLC5A1EPHX2 | |
| SCHEMBL9030754 | 0.83 | LGALS9 (0.41) | SLC5A2 | |
| SCHEMBL10148704 | 0.82 | SLC6A2 (0.49) | SLC5A2SLC5A1 | |
| SCHEMBL6559086 | 0.82 | SLC6A2 (0.49) | SLC5A2SLC5A1 | |
| SCHEMBL6559094 | 0.82 | SLC6A2 (0.49) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |