Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 8/20 | 0.67 |
| ▸ | KIF20A | O95235 | 6/20 | 0.67 |
| ▸ | CLK1 | P49759 | 7/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CPT1A | P50416 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728478 | 0.90 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL2728482 | 0.90 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL2728481 | 0.90 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL2725493 | 0.90 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL2725494 | 0.90 | DYRK1A (0.67) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL3434269 | 0.84 | DYRK1A (0.60) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL3434452 | 0.81 | DYRK1A (0.56) | DYRK1AKIF20ACLK1NR4A2CPT1A | |
| SCHEMBL2725011 | 0.80 | DYRK1A (1.00) | DYRK1AKIF20ACLK1MEN1KMT2A | |
| SCHEMBL2725005 | 0.80 | DYRK1A (1.00) | DYRK1AKIF20ACLK1MEN1KMT2A | |
| SCHEMBL2726433 | 0.80 | KIF20A (0.59) | DYRK1AKIF20ACLK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014115071-A1 | KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-31 | — | — | WO | disclosed |