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Sugi Predict / Targets / KIF20A

KIF20A

Kinesin-like protein KIF20A · O95235 · KIF20A on Sugi Atlas →

1,816 patent compounds predicted against KIF20A, 1,368 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2725524 SCHEMBL2725524 1.00 12/20
SCHEMBL2725529 SCHEMBL2725529 1.00 12/20
SCHEMBL2725764 SCHEMBL2725764 1.00 12/20
SCHEMBL2726001 SCHEMBL2726001 0.77 12/20
SCHEMBL2726006 SCHEMBL2726006 0.77 12/20
SCHEMBL2725671 SCHEMBL2725671 0.73 12/20
SCHEMBL2725676 SCHEMBL2725676 0.73 12/20
SCHEMBL6858032 SCHEMBL6858032 0.69 12/20
SCHEMBL6858038 SCHEMBL6858038 0.69 12/20
SCHEMBL2725053 SCHEMBL2725053 1.00 11/20
SCHEMBL2725057 SCHEMBL2725057 1.00 11/20
SCHEMBL274836 SCHEMBL274836 0.79 11/20
SCHEMBL274837 SCHEMBL274837 0.79 11/20
SCHEMBL2727190 SCHEMBL2727190 0.69 11/20
SCHEMBL2727191 SCHEMBL2727191 0.69 11/20
SCHEMBL8831240 SCHEMBL8831240 0.67 11/20
SCHEMBL8831245 SCHEMBL8831245 0.67 11/20
SCHEMBL2726532 SCHEMBL2726532 0.54 11/20
SCHEMBL2726861 SCHEMBL2726861 0.54 11/20
SCHEMBL2724561 SCHEMBL2724561 1.00 10/20

Clinical trials — most relevant to KIF20A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients PHASE1/PHASE2COMPLETED
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy With GenSci122 in Participants With Advanced Solid Tumors PHASE1RECRUITING
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype EARLY_PHASE1COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Registry and Natural History of Epilepsy-Dyskinesia Syndromes nanRECRUITING
Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry nanUNKNOWN
Hong Kong Spinocerebellar Ataxias Registry nanRECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Core Stability Exercises and Hereditary Ataxia nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay nanNOT_YET_RECRUITING
PCD New Gene Discovery nanCOMPLETED
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS) nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics nanCOMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Characteristics of Episodic Ataxia Syndrome nanCOMPLETED
Gait in Rare Diseases nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a KIF20A binder may also engage these)

ProteinNameSimilarity
P97329 — 0.999 P97329 →
Q29RT6 — 0.999 Q29RT6 →
Q7M6Z5 — 0.995 Q7M6Z5 →
Q8BMD7 — 0.995 Q8BMD7 →
F4IJK6 — 0.995 F4IJK6 →
Q80WE4 — 0.995 Q80WE4 →
Q12756 — 0.994 Q12756 →
Q922S8 — 0.994 Q922S8 →
A0JN40 — 0.994 A0JN40 →
Q86VH2 — 0.993 Q86VH2 →
Q90640 — 0.993 Q90640 →
Q80TF6 — 0.992 Q80TF6 →
Q94LW7 — 0.992 Q94LW7 →
Q9S7P3 — 0.992 Q9S7P3 →
Q8GS71 — 0.992 Q8GS71 →
Q9EQW7 — 0.992 Q9EQW7 →
Q0E2L3 — 0.992 Q0E2L3 →
Q60575 — 0.992 Q60575 →
B9FAF3 — 0.992 B9FAF3 →
SEPTIN8 Septin-8 0.991 landscape →
BRPF3 Bromodomain and PHD finger-containing protein 3 0.991 landscape →
Q91WD7 — 0.991 Q91WD7 →
Q5ZLK6 — 0.990 Q5ZLK6 →
Q99P99 — 0.990 Q99P99 →
Q6IVY4 — 0.990 Q6IVY4 →
B7ZC32 — 0.990 B7ZC32 →
Q651Z7 — 0.990 Q651Z7 →
Q8LNZ2 — 0.990 Q8LNZ2 →
Q8S949 — 0.990 Q8S949 →
Q9H1H9 — 0.990 Q9H1H9 →