SCHEMBL15907934

SCHEMBL15907934

Brc1ccc(C=Cc2ccc(C=CC=C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 1/20 0.45
MAPT P10636 3/20 0.43
GPR183 P32249 1/20 0.42
EGFR P00533 1/20 0.41
HDAC1 Q13547 1/20 0.41
MAOB P27338 1/20 0.40
P4HB P07237 1/20 0.40
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
CYP2C19 P33261 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15907942 0.90 ESR1 (0.46) CYP1B1MAPTGPR183EGFRKMT2A
SCHEMBL2044828 0.89 MAOB (0.50) CYP1B1MAPTHDAC1MAOBKMT2A
SCHEMBL2044831 0.89 MAOB (0.50) CYP1B1MAPTHDAC1MAOBKMT2A
SCHEMBL4595081 0.85 MAOB (0.58) CYP1B1MAPTHDAC1MAOBKDM4E
SCHEMBL15907921 0.85 TTR (0.38) CYP1B1MAPTGPR183EGFRP4HB
SCHEMBL393155 0.85 MAOB (0.56) CYP1B1MAPTHDAC1MAOBKDM4E
SCHEMBL11415300 0.85 MAOB (0.56) CYP1B1MAPTHDAC1MAOBKDM4E
SCHEMBL15907940 0.83 GPR183 (0.45) MAPTGPR183MAOBKDM4EALDH1A1
SCHEMBL15907941 0.82 MAOB (0.40) CYP1B1MAPTHDAC1MAOBKMT2A
SCHEMBL15900234 0.82 MAOB (0.53) CYP1B1EGFRHDAC1MAOBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9128393-B2 Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-09-08 US disclosed
US-20140213822-A1 TRIPHENYLAMINE DERIVATIVE, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-31 US disclosed